Epigenetics/Functional Genomics

Postdoctoral Research/Visiting Fellowships are immediately available in Raja Jothi's laboratory at the National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH) to study mechanisms of gene regulation. Dr. Jothi's group is interested in understanding how transcription regulators and chromatin modifications regulate gene expression programs during cellular development and differentiation. Currently, the group is focused on mapping and characterizing regulatory elements and epigenomes in human and mouse embryonic/hematopoietic stem cells, T cells, and cancer cells.

Successful candidates will undertake exciting new projects in the general areas of Functional Genomics and Epigenomics incorporating sequence- and array-based genomic profiling (ChIP-Seq, RNA-Seq, microarrays, etc), in combination with more traditional approaches to characterize DNA, RNA and proteins. He/She will work closely with experimental biologists in Paul Wade's lab at NIEHS, NIH.

Access to core facilities (Next Generation Sequencing, Microarrays, Immunohistochemistry, Flow Cytometry, Histology, transgenic/knockout mice core, Viral Vectors, etc) offers the trainee wide latitude in the design and pursuit of their research questions.

Qualifications: Candidates must be completing or should have obtained a Ph.D. or M.D. degree in Molecular Biology, Cell Biology, Biochemistry, Genetics or a related discipline within the last three years. The candidate should have strong background in molecular biology, and/or protein biochemistry. Experience in Chromatin immunoprecipitation (ChIP) and RNAi are highly desirable. Excellent communications skills and the ability to work with an highly interactive, interdisciplinary team of researchers are essential.

Location: NIEHS main campus in the Research Triangle Park (RTP), North Carolina. The RTP is the largest research park in US located between Raleigh, Durham, and Chapel Hill, and is within ~12 miles from Duke University, University of North Carolina-Chapel Hill, and North Carolina State University.

Scientist magazine ranks NIEHS as the 16th best workplace for Postdocs, ahead of the National Cancer Institute (NCI), which is ranked at number 19, and NIH, which came in at 32

Stipend/Salary & Benefits: Successful candidates will be offered competitive stipend/salary (at least $46,800 per year) commensurate with number of years of postdoctoral experience and accomplishments. Benefits package will include health insurance, and travel support for one meeting each year. A 401K plan with matching contributions will be offered to those hired as Research Fellows.


Disclaimer: The views and opinions expressed on this website do not state or reflect those of the U.S. Government, DHHS, NIH, or NIEHS.

This file was last updated on Jan 29, 2010. Copyright 2006-2010, Raja Jothi. All rights reserved.